Author's details

Name: Joyce Miller
Date registered: April 3, 2012

Latest posts

  1. Drugs past their expiration date — January 27, 2016
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  3. Understanding variation in 30-day surgical readmission in the era of accountable care: effect of the patient, surgeon, and surgical subspecialties — January 27, 2016
  4. Evidence for a standardized preadmission showering regimen to achieve maximal antiseptic skin surface concentrations of chlorhexidine gluconate, 4%, in surgical patients — January 27, 2016
  5. Consensus statement by the American Assn of Clinical Endocrinologists and Amer Coll Endocrinology on the comprehensive type 2 diabetes management algorithm — January 13, 2016

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  1. “PubMed Clinic” – Learn how to use our intranet electronic medical library and tie it into PubMed searching — 1 comment
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Drugs past their expiration date

by jmiller on January 27, 2016

According to The Medical Letter (Dec. 7), “When no suitable alternative is available, outdated drugs may be effective.  How much potency they retain varies with the drug, the lot, the preservatives (if any), and the storage conditions, especially heat and humidity; many solid dosage formulations stored under reasonable conditions in their original unopened containers retain up to 90% or greater of their potency for at least 5 years after the expiration date on the label, and sometimes much longer.  solutions and suspension are generally less stable.  There are no reports of toxicity from degradation products of currently available drugs.  Click here to read full text.