“When analyzed at the county level, the clearest result of mammography screening is the diagnosis of additional small cancers. Furthermore, there is no conocomitant decline in the detection of larger cancers, which might explain the absence of any significant difference in the overall rate of death from the disease. Together, these findings suggest widespread overdiagnosis. As is the case with screening in general, the balance of benefits and harms is likely to be most favorable when screening is directed to those at high risk.” (JAMA Intern Med, early online) Click here to read full-text.
News You Can Use
“The FDA has approved edoxaban (Savaysa), a once-daily, oral, direct factor Xa inhibitor, for treatment of venous thromboembolism (VTE) and for prevention of stroke and systematic embolism in patients with nonvalvular atrial fibrillation. It is the fourth new oral anticoagulant to be approved for VTE and non-valvular atrial fibrillation.” (Jama, July 7) To read full-text, click here.
What is VisualDx?
VisualDx is one of the most widely used medical apps in the world to improve diagnostic accuracy, medical education and patient education. VisualDx is already licensed by more than 50% of US medical schools including Harvard, Yale, Cornell, University of Pennsylvania, UCLA, USC, UNC, University of Washington, and many more. Over the past 3 years, it has been voted among the top favorite apps multiple times at Harvard and University of Pennsylvania. It is one of the top rated databases in KLAS, which is the Consumer Reports of databases. It will give any visual pictures connected with a disease, as well as the new ICD10 codes; pearls of wisdom; treatment and references connected with dresources. There is also a mobile app. Questions: call Joyce Miller, Medical Librarian ext. 4877.
Innovation in maternal-fetal therapy: a positon statement of the NA Fetal Therapy Network and Expanded carrier screening in reproductive medicine – points to consider: A joint statementby jmiller on June 26, 2015
Innovative medical therapy often occupies an uncomfortable space between formal research and established clinical practice.. Because fetal medicine is unique in that other fields do not have to consider the well being of two individuals at the same time, the North American Fetal Therapy Network offers these expanded guidelines. Expanded genetic carrier screening in reproductive medicine is provided in the Joint Statement of ACOG, the Society for Maternal-Fetal Medicine, and the National Society of Genetic Counselors. (Obstet Gynecol, March) Click here to read full-text.
ACOG Practice Bulletin148: Thyroid disease in pregnancy and ACOG Practice Bulletin 149: Endometrial Cancerby jmiller on June 26, 2015
ACOG issued two new Practice Bulletins (Obstet Gynecol, April) . The thyroid bulletin expresses concerns over uncontrolled thyrotoxicosis and hypothyroidism having adverse pregnancy outcomes. It also impacts fetal development. In addition, medications that affect the maternal thyroid gland can cross the placenta and affect the fetal thyroid glancd. Endometrial carcinoma is the most commonly diagnosed gynecologic malignancy. This article reviews the epidemiology, pathophysiology, and diagnostic and management startegies for this type of cancer. To read full-text, click here.
An official ATS/AACN/ACCP/ESICMSCCM Policy Statement: Responding to requests for potentially inappropriate treatments in Intensive Care Unitsby jmiller on June 25, 2015
Concludes: “The multisociety statement on responding to requests for potentially inapproprate treatments in intensive care units provides guidance for clinicians to prevent and manage disputes in patients with advanced critical illness.“ Am J Resp Crit Care Med, June 1) Click here to read full-text.
Concludes: “There was moderate-quality evidence to support the use of cannabinoids for the treatment of chronic pain and spasticity. There was low-quality evidence suggesting that cannabinoids were associated with improvements in nausea and vomiting due to chemotherapy, weight gain in HIV infections, sleep disorders, and Tourette syndrome. Cannabinoids were associated with an increased risk of short-term adverse effects. (NEJM, June) Editorial and “Medical marijuana for treatment of chronic pain and other medical and psychiatric problems: a clinical review” also attached. Click here to read full-text.
“The evolution of modern interventional radiology beganover half century ago with a simple question. Was it possible to use the same diagnostic imaging tools that had revolutionizedthe practice of medicine to guide the real-time treatment of disease? This disruptive concept led to rapid treatment advances in every organ system of the body. It became clear that by utilizing imaging some patients could undergo targeted procedures, eliminating the need for major surgery, while others could undergo procedures for previously unsolvable problems. The breadth of these changes now encompasses all of medicine and has forever changed the way we think about disease. In this brief reviewarticle, major advances in the field, as chronicled in the pages of Radiology, will be chronicled”. Click here to read full article.