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Effectiveness and harms of recombinant human bone morphogenic protein-2 in spine fusion: a systematic review and meta-analysis

by jmiller on June 21, 2013

This is a “hot” topic in the orthopedic world… Article concludes:  “In spinal fusion, rhBMP-2 has no proven clinical advantage over bone graft and may be associated with important harms, making it difficult to identify clear indications for rhBMP-w.  Earlier disclosure of all relevant data would have better informaed clinicians and the public than the initial published trial reports did.  (Ann Intern Med, June 18) Click here to read full-text.

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