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Breast Cancer

 

AAMC Breast Trials

Breast Cancer Research Program

 

Breast Surgery
Study Status Study Title Principal Investigator
Active-Enrolling Walter Reed   Tissue and Blood Library Establishment for Molecular, Biochemical and Histologic Study of Breast Disease PI: Lorraine Tafra
Active-Enrolling Nipple Sparing vs. Non-Nipple Sparing Mastectomy: Patient Outcomes and Surgeon Ergonomics PI: Lorraine Tafra
Active-Enrolling BioZorb™ Registry: Use of the BioZorb™ implant to delineate the tumor excision site following lumpectomy PI: Lorraine Tafra
Active-Enrolling AAMC Breast Cancer Recurrence Registry PI: Rubie Sue Jackson
Active-Enrolling AFT-25 COMET- Comparison of Operative to Monitoring and Endocrine Therapy for Low Risk DCIS PI: Wen Liang

 

Radiation Oncology
Trial Link Study Status Study Title Principal Investigator
NSABP-B51 Active-Enrolling NSABP B-51: A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chest Wall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy PI: Mary Young
A011202 Active-Enrolling A RANDOMIZED PHASE III TRIAL COMPARING AXILLARY LYMPH NODE DISSECTION TO AXILLARY RADIATION IN BREAST CANCER PATIENTS (CT1-3 N1) WHO HAVE POSITIVE SENTINEL LYMPH NODE DISEASE AFTER NEOADJUVANT CHEMOTHERAPY

 

PI: Mary Young

 

Medical Oncology
Trial Link Study Status Study Title Principal Investigator
MATCH Active-Enrolling Histologically documented solid tumors or histologically confirmed diagnosis of lymphoma or multiple myeloma that has progressed following at least one line of standard systemic therapy and/or for whose disease no standard treatment exists that has been shown to prolong survival. PI: Carol Tweed
S1207 Active-Enrolling Phase III Randomized, Placebo-Controlled Clinical Trial Evaluating the Use of adjuvant Endocrine Therapy +/- One Year of Everolimus in Patients with High-Risk, Hormone Receptor-Positive and HER2/neu Negative Breast Cancer. e3 Breast Cancer Study- evaluating everolimus with endocrine therapy. PI: Carol Tweed
E2112  

Active-

Enrolling

 

A Randomized Phase III Trial of Endocrine Therapy plus Entinostat/Placebo in Patients with Hormone Receptor-Positive Advanced Breast Cancer PI: Jeanine Werner
METRIC  

Active-Enrolling

 

A Randomized Multicenter Pivotal Study of CDX-011 (CR011-vcMMAE) in Patients with Metastatic, GPNMB Over-Expressing, Triple-Negative Breast Cancer (The “METRIC” Study) PI: David Weng
PALLAS Active-Enrolling PALLAS: A randomized phase III trial of Palbociclib with standard adjuvant endocrine therapy versus standard adjuvant endocrine therapy alone for hormone receptor positive (HR+) / human epidermal growth factor receptor 2 (HER2)-negative early breast cancer

 

PI: Carol Tweed

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Other
Trial Link Study Status Study Title Principal Investigator
A011401 Active-Enrolling Breast Cancer Weight Loss Study (BWEL Study) PI: Mary Young
TBCRC 040 Active-Enrolling Monitoring Plasma Tumor DNA in Early-Stage Breast Cancer PI:   Carol Tweed

 

 

 

Our Studies